⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1120435 | 0.74 | — | — | |
| SCHEMBL8169446 | 0.73 | SOS1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL1992388 | 0.72 | SOS1 (0.52) | — | |
| Iodide SCHEMBL22031615 | 0.72 | SOS1 (0.52) | — | |
| SCHEMBL7029146 | 0.72 | — | — | |
| Ammonia Solution, Strong SCHEMBL27616014 | 0.72 | SOS1 (0.52) | — | |
| Hydrochloric Acid SCHEMBL3881741 | 0.72 | SOS1 (0.52) | — | |
| SCHEMBL24175908 | 0.70 | — | — | |
| SCHEMBL13770606 | 0.70 | — | — | |
| SCHEMBL1157614 | 0.70 | SOS1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11292786-B2 | Pyrimidine compounds and pharmaceutical compositions for preventing or treating cancers including the same | HANMI PHARM. CO., LTD. (KR) | 2022-04-05 | — | — | US | disclosed |