Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458174 | 1.00 | HPGD (0.66) | HPGDALDH1A1HTTKMT2AGAA | |
| SCHEMBL31388324 | 0.89 | HPGD (0.80) | HPGDALDH1A1HTTKMT2AGAA | |
| SCHEMBL3822985 | 0.89 | HPGD (0.80) | HPGDALDH1A1HTTKMT2AGAA | |
| SCHEMBL27920292 | 0.86 | HPGD (0.62) | HPGDALDH1A1HTTKMT2AGAA | |
| SCHEMBL13299603 | 0.84 | HPGD (0.68) | HPGDALDH1A1HTTKMT2AGAA | |
| SCHEMBL25347923 | 0.82 | HPGD (0.66) | HPGDALDH1A1HTTKMT2AGAA | |
| SCHEMBL458501 | 0.82 | ALDH1A1 (0.61) | HPGDALDH1A1HTTKMT2AGAA | |
| SCHEMBL1396138 | 0.81 | ALDH1A1 (0.64) | HPGDALDH1A1HTTKMT2AGAA | |
| SCHEMBL29654196 | 0.81 | ALDH1A1 (0.64) | HPGDALDH1A1HTTKMT2AGAA | |
| SCHEMBL17956756 | 0.81 | GAA (0.71) | HPGDALDH1A1HTTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086079-A1 | DERIVATIVE OF SEMICARBAZONE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF | 고려대학교 산학협력단 | 2022-04-28 | — | — | WO | disclosed |