Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.80 |
| ▸ | GAA | P10253 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31388324 | 1.00 | HPGD (0.80) | HPGDGAAALDH1A1HTTKMT2A | |
| SCHEMBL17956756 | 0.91 | GAA (0.71) | HPGDGAAALDH1A1HTTKMT2A | |
| SCHEMBL17079608 | 0.91 | ALDH1A1 (0.71) | HPGDGAAALDH1A1HTTKMT2A | |
| SCHEMBL13299603 | 0.90 | HPGD (0.68) | HPGDGAAALDH1A1HTTKMT2A | |
| SCHEMBL25347923 | 0.89 | HPGD (0.66) | HPGDGAAALDH1A1HTTKMT2A | |
| SCHEMBL29488200 | 0.89 | HPGD (0.66) | HPGDGAAALDH1A1HTTKMT2A | |
| SCHEMBL458174 | 0.89 | HPGD (0.66) | HPGDGAAALDH1A1HTTKMT2A | |
| SCHEMBL25517519 | 0.87 | HPGD (0.63) | HPGDGAAALDH1A1HTTKMT2A | |
| SCHEMBL27720250 | 0.87 | ALDH1A1 (0.73) | HPGDGAAALDH1A1HTTKMT2A | |
| SCHEMBL3129401 | 0.86 | HPGD (0.66) | HPGDGAAALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| EP-1479370-B1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | USA (US) | 2009-07-08 | — | — | EP | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| US-7169815-B2 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2007-01-30 | — | — | US | disclosed |
| EP-1280495-B1 | 3-METHOXYBENZYL THIOUREA DERIVATIVES AND IMPROVED LIPID COMPOSITIONS CONTAINING SAME | US AGRICULTURE (US) | 2006-11-22 | — | — | EP | disclosed |
| US-7053243-B2 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION (US) | 2006-05-30 | — | — | US | disclosed |
| EP-1479370-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | The United States of America (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20040030188-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | SECRETARY OF AGRICULTURE | 2004-02-12 | — | — | US | disclosed |
| US-6653505-B2 | Oxidation resistance | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-11-25 | — | — | US | disclosed |
| US-20030204113-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-10-30 | — | — | US | disclosed |
| US-6586628-B2 | Oxidation resistance | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-07-01 | — | — | US | disclosed |
| EP-1280495-A2 | 3-METHOXYBENZYL THIOUREA DERIVATIVES AND IMPROVED LIPID COMPOSITIONS CONTAINING SAME | Abbott, Thomas, P. (US) | 2003-02-05 | — | — | EP | disclosed |
| US-20020147365-A1 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION | 2002-10-10 | — | — | US | disclosed |
| US-20010056205-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION | 2001-12-27 | — | — | US | disclosed |
| WO-2001085681-A2 | 3-METHOXYBENZYL THIOUREA DERIVATIVES AND IMPROVED LIPID COMPOSITIONS CONTAINING SAME | THE FANNING CORPORATION (US) | 2001-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030188-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | HPGD 2107/4885GAA 1380/4885ALDH1A1 754/4885 |
| US-20010056205-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | HPGD 2107/4885GAA 1380/4885ALDH1A1 754/4885 |
| US-20020147365-A1 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | HPGD 2107/4885GAA 1380/4885ALDH1A1 754/4885 |
| US-20030204113-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | HPGD 2107/4885GAA 1380/4885ALDH1A1 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.