Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.54 |
| ▸ | BAD | Q92934 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.38 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNK18 | Q7Z418 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17698887 | 1.00 | BCL2L1 (0.54) | BCL2L1BADCYP2A6MAOAMAOB | |
| SCHEMBL4974372 | 0.95 | BCL2L1 (0.60) | BCL2L1BADCYP2A6MAOAMAOB | |
| Bromide SCHEMBL7104246 | 0.92 | BCL2L1 (0.58) | BCL2L1BADCYP2A6MAOAMAOB | |
| SCHEMBL21401875 | 0.84 | PRCP (0.58) | BCL2L1BADCYP2A6MAOAMAOB | |
| Phosphoric Acid SCHEMBL3922743 | 0.83 | BCL2L1 (0.53) | BCL2L1BADCYP2A6MAOAMAOB | |
| SCHEMBL31722376 | 0.81 | BCL2L1 (0.42) | BCL2L1BADCYP2A6MAOAMAOB | |
| SCHEMBL18647408 | 0.81 | BCL2L1 (0.42) | BCL2L1BADCYP2A6MAOAMAOB | |
| SCHEMBL23961401 | 0.81 | BCL2L1 (0.39) | BCL2L1BADCYP2A6MAOAMAOB | |
| SCHEMBL18647471 | 0.81 | BCL2L1 (0.39) | BCL2L1BADCYP2A6MAOAMAOB | |
| SCHEMBL3453685 | 0.81 | ALDH1A1 (0.43) | BCL2L1BADCYP2A6MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590062-B2 | PD-1/PD-L1 inhibitors | GILEAD SCIENCES, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| CN-114206338-A | Indanes as PD-L1 inhibitors | 凯莫森特里克斯股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12590062-B2 | PD-1/PD-L1 inhibitors | CD274, PDCD1LG2, PDCD1 | BCL2L1 365/4885BAD 550/4885CYP2A6 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.