Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307895 | 1.00 | MEN1 (0.50) | MEN1KMT2AMAPTPLA2G1BDUSP3 | |
| SCHEMBL28738664 | 0.86 | BRD4 (0.46) | MAPTPKMPOLBNPC1RAB9A | |
| SCHEMBL28738684 | 0.84 | MAPT (0.54) | MEN1KMT2AMAPTPLA2G1BDUSP3 | |
| SCHEMBL29488257 | 0.84 | MAPT (0.54) | MEN1KMT2AMAPTPLA2G1BDUSP3 | |
| SCHEMBL29488269 | 0.82 | MAPT (0.45) | MAPTALDH1A1 | |
| SCHEMBL28308601 | 0.82 | MAPT (0.45) | MAPTALDH1A1 | |
| SCHEMBL29488268 | 0.82 | MAPT (0.45) | MAPTALDH1A1 | |
| SCHEMBL29488270 | 0.80 | XDH (0.50) | MEN1KMT2AMAPTPLA2G1BDUSP3 | |
| SCHEMBL28738673 | 0.80 | XDH (0.50) | MEN1KMT2AMAPTPLA2G1BDUSP3 | |
| SCHEMBL28308718 | 0.79 | EGFR (0.53) | KMT2AMAPTRAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897008-B | 2-benzoyl-6-amino-4 (3H) -quinazolinone derivative and synthesis method and application thereof | 中南大学 | 2022-05-03 | — | — | CN | disclosed |