Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.45 |
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488269 | 1.00 | MAPT (0.45) | MAPTLMNATP53BTKHTT | |
| SCHEMBL28308601 | 1.00 | MAPT (0.45) | MAPTLMNATP53BTKHTT | |
| SCHEMBL28738664 | 0.87 | BRD4 (0.46) | MAPTHTTALDH1A1 | |
| SCHEMBL29488254 | 0.82 | MEN1 (0.50) | MAPTALDH1A1 | |
| SCHEMBL28307895 | 0.82 | MEN1 (0.50) | MAPTALDH1A1 | |
| SCHEMBL28308718 | 0.80 | EGFR (0.53) | MAPTLMNATP53HTTL3MBTL1 | |
| SCHEMBL28738669 | 0.80 | MGLL (0.46) | MAPTHTTALDH1A1MGLL | |
| SCHEMBL29488256 | 0.80 | MGLL (0.46) | MAPTHTTALDH1A1MGLL | |
| SCHEMBL28940483 | 0.78 | FFAR1 (0.54) | MAPTLMNATP53HTTALDH1A1 | |
| SCHEMBL29488265 | 0.78 | MAPT (0.46) | MAPTLMNAHTTALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897008-B | 2-benzoyl-6-amino-4 (3H) -quinazolinone derivative and synthesis method and application thereof | 中南大学 | 2022-05-03 | — | — | CN | disclosed |