Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28738700 | 1.00 | ALDH1A1 (0.52) | ALDH1A1BRD4TTRMAPTMEN1 | |
| SCHEMBL28738671 | 0.84 | MAPT (0.51) | ALDH1A1BRD4MAPTMEN1KMT2A | |
| SCHEMBL29488258 | 0.83 | BRD4 (0.52) | ALDH1A1BRD4MAPTMEN1KMT2A | |
| SCHEMBL28738687 | 0.83 | BRD4 (0.52) | ALDH1A1BRD4MAPTMEN1KMT2A | |
| SCHEMBL29488257 | 0.82 | MAPT (0.54) | ALDH1A1MAPTMEN1KMT2APLA2G1B | |
| SCHEMBL28738684 | 0.82 | MAPT (0.54) | ALDH1A1MAPTMEN1KMT2APLA2G1B | |
| SCHEMBL28738676 | 0.82 | MAPT (0.59) | BRD4MAPTMEN1KMT2APLA2G1B | |
| SCHEMBL28738677 | 0.79 | MAPT (0.48) | ALDH1A1BRD4MAPTMEN1KMT2A | |
| SCHEMBL8201681 | 0.78 | MEN1 (0.58) | ALDH1A1MAPTMEN1KMT2APLA2G1B | |
| SCHEMBL28738683 | 0.76 | ABCG2 (0.48) | MAPTMEN1KMT2APLA2G1BDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897008-B | 2-benzoyl-6-amino-4 (3H) -quinazolinone derivative and synthesis method and application thereof | 中南大学 | 2022-05-03 | — | — | CN | disclosed |