Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28738687 | 1.00 | BRD4 (0.52) | BRD4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28738700 | 0.83 | ALDH1A1 (0.52) | BRD4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29488267 | 0.83 | ALDH1A1 (0.52) | BRD4TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28738695 | 0.82 | BRD4 (0.51) | BRD4MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL28738679 | 0.80 | TOP2A (0.54) | BRD4TSHRMEN1KMT2APOLB | |
| SCHEMBL29488265 | 0.79 | MAPT (0.46) | BRD4TSHRMEN1KMT2APOLB | |
| SCHEMBL29488264 | 0.79 | MAPT (0.46) | BRD4TSHRMEN1KMT2APOLB | |
| SCHEMBL28308709 | 0.79 | MAPT (0.46) | BRD4TSHRMEN1KMT2APOLB | |
| SCHEMBL28738662 | 0.77 | BRD4 (0.46) | BRD4MEN1KMT2ANPC1TOP2A | |
| SCHEMBL17786541 | 0.76 | GUSB (0.71) | CYP1A2MEN1KMT2APOLBCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897008-B | 2-benzoyl-6-amino-4 (3H) -quinazolinone derivative and synthesis method and application thereof | 中南大学 | 2022-05-03 | — | — | CN | disclosed |