Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | IDE | P14735 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305248 | 1.00 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1PKMKDM4ESMN1; SMN2 | |
| SCHEMBL1305250 | 1.00 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1PKMKDM4ESMN1; SMN2 | |
| SCHEMBL1306376 | 0.92 | KDM4E (0.50) | L3MBTL1ALDH1A1PKMKDM4ESMN1; SMN2 | |
| SCHEMBL1306379 | 0.92 | KDM4E (0.50) | L3MBTL1ALDH1A1PKMKDM4ESMN1; SMN2 | |
| SCHEMBL1306260 | 0.91 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1PKMKDM4ESMN1; SMN2 | |
| SCHEMBL1306262 | 0.91 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1PKMKDM4ESMN1; SMN2 | |
| SCHEMBL1306647 | 0.86 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1PKMKDM4ESMN1; SMN2 | |
| SCHEMBL1306640 | 0.86 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1PKMKDM4ESMN1; SMN2 | |
| SCHEMBL1306643 | 0.86 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1PKMKDM4ESMN1; SMN2 | |
| SCHEMBL1306264 | 0.84 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1PKMKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026544-A1 | PHARMACEUTICAL COMPOSITION COMPRISING HDAC INHIBITOR AND ANTI-PD1 ANTIBODY OR ANTI PD-L1 ANTIBODY | Crystalgenomics, Inc. (KR) | 2022-07-13 | — | — | EP | claimed |
| CN-114340672-A | Pharmaceutical composition comprising an HDAC inhibitor and an anti-PD 1 antibody or an anti-PD-L1 antibody | 晶体基因技术株式会社 | 2022-04-12 | — | — | CN | claimed |
| CN-112930177-B | Pharmaceutical compositions containing alkylcarbamoyl naphthoyl octenoyl hydroxyamide phosphate, tartrate or combinations thereof and methods of making the same | 晶体基因技术株式会社 | 2024-01-30 | — | — | CN | disclosed |
| EP-4155292-A1 | METHOD FOR PRODUCING PHARMACEUTICALLY ACCEPTABLE SALT OF ALKYLCARBAMOYL NAPHTHALENYLOXY OCTENOYLHYDROXYAMIDE | Crystalgenomics, Inc. (KR) | 2023-03-29 | — | — | EP | disclosed |
| EP-4026544-A1 | PHARMACEUTICAL COMPOSITION COMPRISING HDAC INHIBITOR AND ANTI-PD1 ANTIBODY OR ANTI PD-L1 ANTIBODY | Crystalgenomics, Inc. (KR) | 2022-07-13 | — | — | EP | disclosed |
| CN-114340672-A | Pharmaceutical composition comprising an HDAC inhibitor and an anti-PD 1 antibody or an anti-PD-L1 antibody | 晶体基因技术株式会社 | 2022-04-12 | — | — | CN | disclosed |
| CN-110740989-B | Pharmaceutically acceptable salts of alkylcarbamoylnaphthoxyoctenoylhydroxyamides or derivatives thereof and process for preparing the same | 晶体基因技术株式会社 | 2022-03-08 | — | — | CN | disclosed |