Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 9/20 | 0.52 |
| ▸ | THRB | P10828 | 9/20 | 0.52 |
| ▸ | CTSK | P43235 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488645 | 0.89 | THRA (0.57) | THRATHRBKMT2A | |
| SCHEMBL29488654 | 0.89 | THRA (0.54) | THRATHRBKMT2A | |
| SCHEMBL29488650 | 0.88 | THRA (0.55) | THRATHRBKMT2A | |
| SCHEMBL29488644 | 0.79 | KMT2A (0.47) | CTSKKMT2A | |
| SCHEMBL24821078 | 0.78 | THRA (0.65) | THRATHRBKMT2A | |
| SCHEMBL29488657 | 0.77 | THRA (0.57) | THRATHRBKMT2A | |
| SCHEMBL24600346 | 0.77 | THRA (0.48) | THRATHRBCTSKKMT2A | |
| SCHEMBL29488653 | 0.77 | THRA (0.56) | THRATHRB | |
| SCHEMBL29488640 | 0.76 | THRA (0.59) | THRATHRB | |
| SCHEMBL23168737 | 0.73 | THRA (0.46) | THRATHRBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068915-A1 | 6-OXO-1,6-DIHYDROPYRIDAZIN DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2022-04-07 | — | — | WO | disclosed |