Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 13/20 | 0.56 |
| ▸ | THRB | P10828 | 13/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23168714 | 0.83 | THRA (0.54) | THRATHRBCYP2C8CYP2C9 | |
| SCHEMBL29488654 | 0.82 | THRA (0.54) | THRATHRBCYP2C8CYP2C9 | |
| SCHEMBL24821078 | 0.81 | THRA (0.65) | THRATHRBCYP2C8CYP2C9 | |
| SCHEMBL29488657 | 0.79 | THRA (0.57) | THRATHRBCYP2C8CYP2C9 | |
| SCHEMBL29488645 | 0.79 | THRA (0.57) | THRATHRBCYP2C8CYP2C9 | |
| SCHEMBL29488650 | 0.78 | THRA (0.55) | THRATHRBCYP2C8CYP2C9 | |
| SCHEMBL29488640 | 0.78 | THRA (0.59) | THRATHRBCYP2C8CYP2C9 | |
| SCHEMBL29488642 | 0.77 | THRA (0.52) | THRATHRB | |
| SCHEMBL23168716 | 0.76 | THRA (0.56) | THRATHRBCYP2C8CYP2C9 | |
| SCHEMBL23168754 | 0.76 | THRA (0.49) | THRATHRBCYP2C8CYP2C9AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068915-A1 | 6-OXO-1,6-DIHYDROPYRIDAZIN DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2022-04-07 | — | — | WO | disclosed |