Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 19/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19183242 | 0.83 | RORC (0.59) | RORC | |
| SCHEMBL19183259 | 0.79 | RORC (0.62) | RORC | |
| SCHEMBL28569238 | 0.76 | RORC (0.64) | RORC | |
| SCHEMBL20631931 | 0.75 | RORC (1.00) | RORC | |
| SCHEMBL28353018 | 0.71 | RORC (0.66) | RORC | |
| SCHEMBL28909371 | 0.71 | RORC (0.62) | RORC | |
| SCHEMBL23632292 | 0.70 | CA1 (0.72) | RORC | |
| SCHEMBL28349854 | 0.70 | CA2 (0.64) | RORC | |
| SCHEMBL23632544 | 0.70 | RORC (0.61) | RORC | |
| SCHEMBL28266759 | 0.70 | RORC (0.61) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230523-A | Benzimidazole derivatives as modulators of ROR-gamma | 生命医药有限责任公司 | 2022-03-25 | — | — | CN | disclosed |