Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488669 | 0.83 | RORC (0.52) | RORC | |
| SCHEMBL29488674 | 0.83 | RORC (0.52) | RORC | |
| SCHEMBL29488685 | 0.82 | RORC (0.56) | RORC | |
| SCHEMBL30065087 | 0.79 | RORC (0.54) | RORC | |
| SCHEMBL30065584 | 0.78 | RORC (0.55) | RORC | |
| SCHEMBL30485940 | 0.78 | RORC (0.55) | RORC | |
| SCHEMBL18477041 | 0.76 | RORC (0.58) | RORC | |
| SCHEMBL30065086 | 0.76 | RORC (0.51) | RORC | |
| SCHEMBL17711672 | 0.75 | RORC (0.59) | RORC | |
| SCHEMBL17711732 | 0.75 | RORC (0.59) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230523-A | Benzimidazole derivatives as modulators of ROR-gamma | 生命医药有限责任公司 | 2022-03-25 | — | — | CN | disclosed |