Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 16/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065087 | 0.87 | RORC (0.54) | RORCROCK2ROCK1 | |
| SCHEMBL30065136 | 0.84 | RORC (0.53) | RORCLMNAROCK2ROCK1 | |
| SCHEMBL30485945 | 0.84 | RORC (0.53) | RORCLMNAROCK2ROCK1 | |
| SCHEMBL30065086 | 0.83 | RORC (0.51) | RORCLMNA | |
| SCHEMBL30065584 | 0.81 | RORC (0.55) | RORC | |
| SCHEMBL29488682 | 0.78 | RORC (0.53) | RORC | |
| SCHEMBL29488669 | 0.77 | RORC (0.52) | RORC | |
| SCHEMBL29488674 | 0.77 | RORC (0.52) | RORC | |
| SCHEMBL17711672 | 0.77 | RORC (0.59) | RORC | |
| SCHEMBL17711732 | 0.77 | RORC (0.59) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912597-B | ROR gamma inhibitor, preparation method and medical application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-06-13 | — | — | CN | disclosed |