⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL29088489 | 0.97 | ACHE (0.94) | — | |
| Fluoride SCHEMBL21816907 | 0.97 | ACHE (0.94) | — | |
| Ammonia Solution, Strong SCHEMBL4593510 | 0.97 | — | — | |
| SCHEMBL29176814 | 0.97 | — | — | |
| SCHEMBL19260336 | 0.94 | ACHE (0.88) | — | |
| Methylamine SCHEMBL28770711 | 0.94 | ACHE (0.88) | — | |
| Ethyne SCHEMBL28761581 | 0.94 | ACHE (0.88) | — | |
| SCHEMBL28557764 | 0.91 | ACHE (0.83) | — | |
| SCHEMBL28811498 | 0.91 | ACHE (0.83) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12336981-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| CN-222427936-U | Automatic accurate feeding equipment of o-fluorotoluene | 山东福尔有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-222317783-U | Fluorotoluene separation and purification heating equipment | 东至德泰精细化工有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-222317783-U | Fluorotoluene separation and purification heating equipment | 东至德泰精细化工有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-114751882-B | Synthesis method of benzofuran | 南京工业大学 | 2024-02-23 | — | — | CN | disclosed |
| US-20230346753-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | VALO HEALTH, INC. | 2023-11-02 | — | — | US | disclosed |
| CN-219046032-U | Sampling device is used in production of para-fluorotoluene | 射阳县维新科技咨询服务有限公司 | 2023-05-19 | — | — | CN | disclosed |
| WO-2023057401-A1 | METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS | MERCK PATENT GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |
| US-20230110003-A1 | PIPERIDINE DERIVATIVES AND COMPOSITIONS FOR THE INHIBITION OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) | Valo Health, LLC | 2023-04-13 | — | — | US | disclosed |
| US-11547701-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-11479564-B2 | Piperidine derivatives and compositions for the inhibition of nicotinamide phosphoribosyltransferase (NAMPT) | VALO HEALTH, INC. (US) | 2022-10-25 | — | — | US | disclosed |
| WO-2022203074-A1 | FLUORINE-CONTAINING CYCLIC SULFONYLIMIDE SALT, AND METHOD FOR PRODUCING SAME, NON-AQUEOUS ELECTROLYTE, NON-AQUEOUS SECONDARY BATTERY | 旭化成株式会社 | 2022-09-29 | — | — | WO | disclosed |
| CN-114751882-A | Synthetic method of benzofuran | 南京工业大学 | 2022-07-15 | — | — | CN | disclosed |
| US-11279687-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2022-03-22 | — | — | US | disclosed |