Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7613846 | 0.83 | GAA (0.54) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL4805620 | 0.83 | GAA (0.54) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL515913 | 0.76 | GAA (0.57) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL9435291 | 0.76 | GAA (0.57) | GAABCL9CTNNB1KMT2APKM | |
| Water SCHEMBL4754930 | 0.75 | GAA (0.55) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL16922669 | 0.73 | GAA (0.57) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL16671852 | 0.73 | GAA (0.57) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL6564402 | 0.73 | BCL9 (0.61) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL4683792 | 0.72 | GAA (0.60) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL21633908 | 0.72 | MEN1 (0.51) | GAABCL9CTNNB1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12459888-B2 | Isotope-enriched 3-amino-1-propanesulfonic acid derivatives and uses thereof | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2025-11-04 | — | — | US | disclosed |
| US-20240158343-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES AND USES THEREOF | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2024-05-16 | — | — | US | disclosed |
| CN-108623501-B | Isotopically enriched 3-amino-1-propanesulfonic acid derivatives and their use | 润佳（苏州）医药科技有限公司 | 2022-04-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158343-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES AND USES THEREOF | PSEN2, PSEN1, APP | GAA 823/4885BCL9 2890/4885CTNNB1 1238/4885 |
| US-12459888-B2 | Isotope-enriched 3-amino-1-propanesulfonic acid derivatives and uses thereof | PSEN2, PSEN1, APP | GAA 823/4885BCL9 2890/4885CTNNB1 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.