Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.36 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29892015 | 0.94 | KEAP1 (0.44) | KEAP1MAPK8MAPK9MAPK10NMUR2 | |
| SCHEMBL30444128 | 0.92 | NMT1 (0.46) | NMT2NMT1 | |
| SCHEMBL29517196 | 0.91 | MEN1 (0.40) | FURINMEN1KMT2AMAPK8MAPK9 | |
| SCHEMBL30808875 | 0.91 | KEAP1 (0.44) | KEAP1FURINMEN1KMT2AHDAC3 | |
| SCHEMBL29406566 | 0.91 | KEAP1 (0.43) | KEAP1MAPK8MAPK9MAPK10NMUR2 | |
| SCHEMBL29825278 | 0.89 | MEN1 (0.39) | KEAP1MEN1KMT2ATERTMAPK8 | |
| SCHEMBL30974174 | 0.88 | KDM1A (0.38) | KEAP1FURINMEN1KMT2AHDAC3 | |
| SCHEMBL29630736 | 0.88 | KEAP1 (0.39) | KEAP1FURINMEN1KMT2AHDAC3 | |
| SCHEMBL30973948 | 0.88 | MEN1 (0.42) | MEN1KMT2AMAPK8MAPK9MAPK10 | |
| SCHEMBL29689742 | 0.87 | PRCP (0.44) | MEN1KMT2ATERTMAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397460-A | Methods of making cells expressing chimeric antigen receptors | 诺华股份有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-111593035-B | Polypeptides having glucoamylase activity and polynucleotides encoding same | 诺维信公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-116298309-B | High throughput cloning of paired bipartite immunoreceptor polynucleotides and uses thereof | 根路径基因组学公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-4232080-A1 | COMPOSITIONS AND METHODS FOR T-CELL RECEPTOR IDENTIFICATION | Rootpath Genomics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| CN-116298309-A | High throughput cloning of paired bipartite immunoreceptor polynucleotides and uses thereof | 根路径基因组学公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116144706-A | High throughput cloning of paired bipartite immunoreceptor polynucleotides and uses thereof | 根路径基因组学公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-112840031-B | High throughput cloning and use of paired bipartite immunoreceptor polynucleotides | 根路径基因组学公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115397460-A | Methods of making cells expressing chimeric antigen receptors | 诺华股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| EP-4061487-A1 | COMPOSITIONS AND METHODS FOR T-CELL RECEPTOR IDENTIFICATION | Rootpath Genomics, Inc. (US) | 2022-09-28 | — | — | EP | disclosed |
| WO-2022087380-A1 | COMPOSITIONS AND METHODS FOR T-CELL RECEPTOR IDENTIFICATION | ROOTPATH GENOMICS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |