Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | NMUR2 | Q9GZQ4 | 3/20 | 0.37 |
| ▸ | NMUR1 | Q9HB89 | 3/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | RAMP3 | O60896 | 6/20 | 0.37 |
| ▸ | CALCR | P30988 | 6/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29406566 | 0.97 | KEAP1 (0.43) | KEAP1KDM1AMAPK8MAPK9MAPK10 | |
| SCHEMBL29892053 | 0.95 | KEAP1 (0.41) | KEAP1KDM1AMAPK8MAPK9MAPK10 | |
| SCHEMBL29489137 | 0.94 | KEAP1 (0.39) | KEAP1MAPK8MAPK9MAPK10NMUR2 | |
| SCHEMBL29777409 | 0.90 | KEAP1 (0.41) | KEAP1KDM1AMAPK8MAPK9MAPK10 | |
| SCHEMBL29517196 | 0.90 | MEN1 (0.40) | KDM1AMAPK8MAPK9MAPK10 | |
| SCHEMBL30444128 | 0.89 | NMT1 (0.46) | KDM1AMAOBKDM5AKDM1B | |
| SCHEMBL30808875 | 0.89 | KEAP1 (0.44) | KEAP1MAPK8MAPK9MAPK10RAMP3 | |
| SCHEMBL30745230 | 0.89 | MEN1 (0.41) | KEAP1KDM1AMAPK8MAPK9MAPK10 | |
| SCHEMBL30564979 | 0.89 | MEN1 (0.39) | KEAP1KDM1AMAPK8MAPK9MAPK10 | |
| SCHEMBL30974174 | 0.88 | KDM1A (0.38) | KEAP1KDM1AMAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240165006-A1 | DERMATOLOGICAL COMPOSTIONS AND USE THEREOF | BONE SCI. BIO LTD. (IL) | 2024-05-23 | — | — | US | claimed |
| EP-4313105-A1 | DERMATOLOGICAL COMPOSITIONS AND USE THEREOF | Bone Sci. Bio Ltd. (IL) | 2024-02-07 | — | — | EP | claimed |
| US-20230130132-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING AMPHIPHILIC PEPTIDES AND METHODS OF USE THEREOF | BONE SCI. BIO LTD. (IL) | 2023-04-27 | — | — | US | claimed |
| EP-4125993-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING AMPHIPHILIC PEPTIDES AND METHODS OF USE THEREOF | Bone Sci. Bio Ltd. (IL) | 2023-02-08 | — | — | EP | claimed |
| WO-2022201146-A1 | DERMATOLOGICAL COMPOSITIONS AND USE THEREOF | BONE SCI. BIO LTD. (IL) | 2022-09-29 | — | — | WO | claimed |
| US-20240165006-A1 | DERMATOLOGICAL COMPOSTIONS AND USE THEREOF | BONE SCI. BIO LTD. (IL) | 2024-05-23 | — | — | US | disclosed |
| EP-4313105-A1 | DERMATOLOGICAL COMPOSITIONS AND USE THEREOF | Bone Sci. Bio Ltd. (IL) | 2024-02-07 | — | — | EP | disclosed |
| US-20230130132-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING AMPHIPHILIC PEPTIDES AND METHODS OF USE THEREOF | BONE SCI. BIO LTD. (IL) | 2023-04-27 | — | — | US | disclosed |
| EP-4125993-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING AMPHIPHILIC PEPTIDES AND METHODS OF USE THEREOF | Bone Sci. Bio Ltd. (IL) | 2023-02-08 | — | — | EP | disclosed |
| WO-2022201146-A1 | DERMATOLOGICAL COMPOSITIONS AND USE THEREOF | BONE SCI. BIO LTD. (IL) | 2022-09-29 | — | — | WO | disclosed |