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Sugi Predict / Compounds / SCHEMBL29489260

SCHEMBL29489260

SCHEMBL29489260

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 9/20 0.62
▸ OPRM1 P35372 8/20 0.62
▸ OPRK1 P41145 4/20 0.62
▸ TFPI P10646 1/20 0.58
▸ KISS1R Q969F8 4/20 0.55
▸ NPBWR1 P48145 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34468124 0.90 TFPI (0.60) OPRD1OPRM1OPRK1TFPINPBWR1
SCHEMBL29525489 0.90 TFPI (0.63) OPRD1OPRM1OPRK1TFPINPBWR1
SCHEMBL30863947 0.89 TFPI (0.66) OPRD1OPRM1OPRK1TFPI
SCHEMBL31480032 0.89 OPRL1 (0.56) OPRD1OPRM1OPRK1TFPINPBWR1
SCHEMBL29590452 0.89 OPRM1 (0.55) OPRD1OPRM1OPRK1TFPIKISS1R
SCHEMBL29569118 0.89 OPRK1 (0.54) OPRD1OPRM1OPRK1
SCHEMBL30842196 0.88 OPRM1 (0.64) OPRD1OPRM1OPRK1TFPIKISS1R
SCHEMBL29385779 0.88 NPY4R (0.61) OPRK1KISS1R
SCHEMBL29822708 0.88 OPRM1 (0.63) OPRD1OPRM1OPRK1TFPIKISS1R
SCHEMBL30397713 0.88 OPRM1 (0.53) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190952-A1 IL-18 Binding Protein (IL-18BP) and Antibodies for Treating Inflammatory Diseases AB2 BIO SA (CH) 2024-06-13 — — US disclosed
US-11926663-B2 IL-18 binding protein (IL-18BP) and antibodies in inflammatory diseases AB2 BIO SA (CH) 2024-03-12 — — US disclosed
US-11820817-B2 IL-18 binding protein (IL-18BP) and antibodies in inflammatory diseases AB2 BIO SA (CH) 2023-11-21 — — US disclosed
US-20230250164-A1 IL-18 Binding Protein (IL-18BP) In Inflammatory Diseases AB2 BIO SA (CH) 2023-08-10 — — US disclosed
US-11530263-B2 IL-18 binding protein (IL-18BP) in inflammatory diseases AB2 BIO SA (CH) 2022-12-20 — — US disclosed
EP-3978526-A1 IL-18 BINDING PROTEIN (IL-18BP) IN INFLAMMATORY DISEASES AB2 Bio SA (CH) 2022-04-06 — — EP disclosed
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