Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.59 |
| ▸ | MAOB | P27338 | 7/20 | 0.59 |
| ▸ | KDM1A | O60341 | 4/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL18281826 | 1.00 | MAOA (0.59) | MAOAMAOBKDM1ADPP4 | |
| SCHEMBL4439368 | 0.98 | MAOA (0.61) | MAOAMAOBKDM1ADPP4 | |
| SCHEMBL5132413 | 0.98 | MAOA (0.61) | MAOAMAOBKDM1ADPP4 | |
| SCHEMBL433971 | 0.80 | MAOA (0.83) | MAOAMAOBKDM1ADPP4 | |
| Hydrochloric Acid SCHEMBL3967040 | 0.78 | MAOA (0.79) | MAOAMAOBKDM1A | |
| SCHEMBL8803044 | 0.78 | MAOA (0.79) | MAOAMAOBKDM1A | |
| SCHEMBL2289825 | 0.78 | MAOA (0.79) | MAOAMAOBKDM1A | |
| SCHEMBL20104709 | 0.78 | MAOA (0.79) | MAOAMAOBKDM1A | |
| SCHEMBL20198582 | 0.78 | MAOA (0.79) | MAOAMAOBKDM1A | |
| SCHEMBL5774057 | 0.77 | KDM1A (0.40) | MAOAMAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976599-A1 | PYRAZOLE-SUBSTITUTED PYRROLIDINONES AS HERBICIDES | FMC CORPORATION (US) | 2022-04-06 | — | — | EP | disclosed |