Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 4/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813767 | 0.82 | MAOA (0.50) | KDM1ARCOR1HTR2ATAAR1IDO1 | |
| SCHEMBL4439368 | 0.78 | MAOA (0.61) | KDM1AMAOAMAOB | |
| SCHEMBL16041470 | 0.78 | MAOA (0.61) | KDM1ARCOR1HTR2ATAAR1IDO1 | |
| SCHEMBL5132413 | 0.78 | MAOA (0.61) | KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL22615595 | 0.77 | MAOA (0.59) | KDM1ARCOR1HTR2ATAAR1IDO1 | |
| Bromide SCHEMBL29489587 | 0.77 | MAOA (0.59) | KDM1AMAOAMAOB | |
| Bromide SCHEMBL18281826 | 0.77 | MAOA (0.59) | KDM1AMAOAMAOB | |
| SCHEMBL14393903 | 0.75 | MME (0.38) | KDM1ARCOR1HTR2ATAAR1IDO1 | |
| SCHEMBL6462848 | 0.74 | KDM1A (0.35) | KDM1ARCOR1HTR2ATAAR1IDO1 | |
| SCHEMBL1773425 | 0.73 | GRIN2D (0.48) | MMESMN1; SMN2NPC1HPGDGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003074534-A9 | REAGENTS FOR ASYMMETRIC ALLYLATION, ALDOL, AND TANDEM ALDOL AND ALLYLATION REACTIONS | UNIV COLUMBIA (US) | 2003-11-20 | — | — | WO | claimed |
| EP-1480988-A4 | REAGENTS FOR ASYMMETRIC ALLYLATION, ALDOL, AND TANDEM ALDOL AND ALLYLATION REACTIONS | UNIV COLUMBIA (US) | 2006-03-29 | — | — | EP | disclosed |
| EP-1480988-A1 | REAGENTS FOR ASYMMETRIC ALLYLATION, ALDOL, AND TANDEM ALDOL AND ALLYLATION REACTIONS | The Trustees of Columbia University in the City of New York (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074534-A1 | REAGENTS FOR ASYMMETRIC ALLYLATION, ALDOL, AND TANDEM ALDOL AND ALLYLATION REACTIONS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-09-12 | — | — | WO | disclosed |