Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22728530 | 1.00 | CRBN (0.49) | CRBNCA9DRD2CHRNA7KCNH2 | |
| Hydrochloric Acid SCHEMBL22721067 | 0.99 | CRBN (0.48) | CRBNCA9DRD2CHRNA7KCNH2 | |
| Bromide SCHEMBL11198697 | 0.73 | CRBN (0.52) | CRBNCA9DRD2NPC1MAPK13 | |
| SCHEMBL15799049 | 0.73 | CRBN (0.55) | CRBNCA9DRD2NPC1MAPK13 | |
| SCHEMBL22721027 | 0.70 | DRD2 (0.43) | DRD2KCNH2NPC1MAPK13MAPK12 | |
| SCHEMBL29489686 | 0.70 | DRD2 (0.43) | DRD2KCNH2NPC1MAPK13MAPK12 | |
| Hydrochloric Acid SCHEMBL22721170 | 0.69 | DRD2 (0.43) | DRD2KCNH2NPC1MAPK13MAPK12 | |
| Hydrochloric Acid SCHEMBL29489681 | 0.69 | DRD2 (0.43) | DRD2KCNH2NPC1MAPK13MAPK12 | |
| SCHEMBL1794604 | 0.69 | CHRNA7 (0.70) | CHRNA7KCNH2 | |
| Hydrochloric Acid SCHEMBL1795082 | 0.68 | CHRNA7 (0.68) | CHRNA7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3978497-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2022-04-06 | — | — | EP | disclosed |