Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ALB | P02768 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.55 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.55 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1478281 | 0.91 | CYP2C9 (0.58) | CYP2C9ALDH1A1KDM4EHSD17B10ALB | |
| SCHEMBL1479347 | 0.88 | CYP2C9 (0.73) | CYP2C9ALDH1A1KDM4EHSD17B10ALB | |
| SCHEMBL136434 | 0.88 | CYP2C9 (0.73) | CYP2C9ALDH1A1KDM4EHSD17B10ALB | |
| SCHEMBL20806 | 0.88 | CYP2C9 (0.73) | CYP2C9ALDH1A1KDM4EHSD17B10ALB | |
| SCHEMBL17132373 | 0.84 | CYP2C9 (0.77) | CYP2C9ALDH1A1KDM4EHSD17B10ALB | |
| Phosphoric Acid SCHEMBL28278851 | 0.82 | CYP2C9 (0.66) | CYP2C9ALDH1A1KDM4EHSD17B10ALB | |
| SCHEMBL1477912 | 0.80 | CYP2C9 (0.63) | CYP2C9ALDH1A1KDM4EHSD17B10ALB | |
| SCHEMBL43382 | 0.77 | CYP2C9 (0.76) | CYP2C9ALDH1A1KDM4EHSD17B10ALB | |
| SCHEMBL1477562 | 0.77 | CYP2C9 (0.76) | CYP2C9ALDH1A1KDM4EHSD17B10ALB | |
| SCHEMBL17132372 | 0.74 | CYP2C9 (0.76) | CYP2C9ALDH1A1KDM4EHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120361022-A | Pharmaceutical composition of mulberry bark glycoside C and 7-hydroxy warfarin and application thereof in acute kidney injury | 江南大学附属医院 | 2025-07-25 | — | — | CN | disclosed |
| CN-120361022-A | Pharmaceutical composition of mulberry bark glycoside C and 7-hydroxy warfarin and application thereof in acute kidney injury | 江南大学附属医院 | 2025-07-25 | — | — | CN | disclosed |
| CN-119136793-A | Bile acids and phenylbutyric acid with CYP P450 or transporter substrates for the treatment of amyotrophic lateral sclerosis | 艾米利克斯制药公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-114008051-B | Pyrazolopyrimidine sulfone inhibitors of JAK kinases and uses thereof | 豪夫迈·罗氏有限公司 | 2024-08-13 | — | — | CN | disclosed |
| WO-2024072778-A1 | METHODS AND COMPOSITIONS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS | AMYLYX PHARMACEUTICALS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| CN-110678467-B | Therapeutic compounds and compositions and methods of use thereof | 豪夫迈·罗氏有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-110650959-B | Therapeutic compounds and compositions and methods of use thereof | 豪夫迈·罗氏有限公司 | 2023-04-18 | — | — | CN | disclosed |
| EP-3986901-A1 | PYRAZOLOPYRIMIDINE SULFONE INHIBITORS OF JAK KINASES AND USES THEREOF | F. Hoffmann-La Roche AG (CH) | 2022-04-27 | — | — | EP | disclosed |
| CN-114008051-A | Pyrazolopyrimidine sulfone inhibitors of JAK kinases and uses thereof | 豪夫迈·罗氏有限公司 | 2022-02-01 | — | — | CN | disclosed |