Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862558 | 1.00 | POLB (0.54) | POLBSMN1; SMN2TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL12136691 | 0.84 | RAB9A (0.57) | POLBSMN1; SMN2TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL9388512 | 0.82 | POLB (0.53) | POLBSMN1; SMN2TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL22862551 | 0.82 | POLB (0.53) | POLBSMN1; SMN2TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL29490174 | 0.82 | POLB (0.53) | POLBSMN1; SMN2TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL7479892 | 0.82 | POLB (0.53) | POLBSMN1; SMN2TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL13156353 | 0.82 | POLB (0.53) | POLBSMN1; SMN2TSHRL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31737865 | 0.81 | POLB (0.51) | POLBSMN1; SMN2TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL13633144 | 0.79 | POLB (0.50) | POLBSMN1; SMN2TSHRL3MBTL1ALDH1A1 | |
| SCHEMBL17229324 | 0.79 | BRD4 (0.51) | POLBSMN1; SMN2TSHRL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |