SCHEMBL29490358

SCHEMBL29490358

Cc1cc(C(=O)NN=Cc2ccccc2O)c2cc(Br)ccc2n1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.60
MEN1 O00255 7/20 0.60
KDM4E B2RXH2 6/20 0.60
HTT P42858 5/20 0.60
MAPT P10636 5/20 0.60
LMNA P02545 4/20 0.60
TDP1 Q9NUW8 3/20 0.60
L3MBTL1 Q9Y468 3/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
ALDH1A1 P00352 2/20 0.58
GAA P10253 1/20 0.58
KDM1A O60341 1/20 0.56
PIK3CG P48736 2/20 0.56
PGR P06401 1/20 0.55
AR P10275 1/20 0.55
HPGD P15428 2/20 0.54
TP53 P04637 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
MAPK1 P28482 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5809172 1.00 KMT2A (0.60) KMT2AMEN1KDM4EHTTMAPT
SCHEMBL21436024 1.00 KMT2A (0.60) KMT2AMEN1KDM4EHTTMAPT
SCHEMBL5809168 1.00 KMT2A (0.60) KMT2AMEN1KDM4EHTTMAPT
SCHEMBL5814633 0.84 KDM4E (0.61) KMT2AMEN1KDM4EHTTMAPT
SCHEMBL5814635 0.84 KDM4E (0.61) KMT2AMEN1KDM4EHTTMAPT
SCHEMBL5813675 0.84 KDM4E (0.56) KMT2AMEN1KDM4EHTTMAPT
SCHEMBL10145127 0.82 KDM4E (0.61) KMT2AMEN1KDM4EHTTMAPT
SCHEMBL5813681 0.81 GAA (0.58) KMT2AMEN1KDM4EHTTMAPT
SCHEMBL5813671 0.81 GAA (0.58) KMT2AMEN1KDM4EHTTMAPT
SCHEMBL5814909 0.77 KDM4E (0.55) KMT2AMEN1KDM4EHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552810-A Placenta culture for isolation of exosomes 细胞结构公司 2025-03-04 CN claimed
CN-119552810-A Placenta culture for isolation of exosomes 细胞结构公司 2025-03-04 CN disclosed
EP-3986381-A1 EXOSOMES FOR DISEASE TREATMENT Celularity Inc. (US) 2022-04-27 EP disclosed
CN-114302731-A Exosomes for treating diseases 细胞结构公司 2022-04-08 CN disclosed