Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 7/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | AGXT | P21549 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22802457 | 1.00 | RIPK1 (0.41) | RIPK1IDO1AGXTBACE1ROCK2 | |
| SCHEMBL29490394 | 1.00 | RIPK1 (0.41) | RIPK1IDO1AGXTBACE1ROCK2 | |
| SCHEMBL31362543 | 0.80 | — | — | |
| SCHEMBL30976535 | 0.80 | IDO1 (0.56) | RIPK1IDO1AGXTBACE1 | |
| SCHEMBL27106193 | 0.80 | IDO1 (0.56) | RIPK1IDO1AGXTBACE1 | |
| SCHEMBL31490382 | 0.77 | APLNR (0.31) | — | |
| SCHEMBL3076782 | 0.77 | BACE1 (0.40) | RIPK1IDO1BACE1 | |
| SCHEMBL17864568 | 0.75 | IDO1 (0.32) | IDO1AGXTBACE1 | |
| SCHEMBL17083346 | 0.75 | RIPK1 (0.45) | RIPK1IDO1AGXT | |
| SCHEMBL27106191 | 0.75 | IDO1 (0.50) | IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986890-A1 | BENZISOXAZOLE SULFONAMIDE DERIVATIVES | Pfizer Inc. (US) | 2022-04-27 | — | — | EP | disclosed |