SCHEMBL29493000

SCHEMBL29493000

CN1c2ccccc2C(C)(C)C12C=Nc1c(ccc3ncccc13)O2

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.72
KDM4E B2RXH2 7/20 0.72
THRB P10828 5/20 0.72
SMN1; SMN2 Q16637 4/20 0.72
ALOX12 P18054 2/20 0.72
L3MBTL1 Q9Y468 2/20 0.72
PKM P14618 2/20 0.72
LMNA P02545 5/20 0.61
GAA P10253 4/20 0.61
HTT P42858 3/20 0.61
ALDH1A1 P00352 3/20 0.61
RECQL P46063 3/20 0.61
TDP1 Q9NUW8 3/20 0.61
HPGD P15428 2/20 0.61
MAPK1 P28482 2/20 0.61
POLB P06746 1/20 0.61
NPSR1 Q6W5P4 3/20 0.57
BLM P54132 2/20 0.57
CYP3A4 P08684 2/20 0.57
CYP2C9 P11712 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7117468 1.00 MAPT (0.72) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL10552518 0.88 MAPT (0.55) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL2397763 0.86 MAPT (0.54) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL13809573 0.86 MAPT (0.82) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL13809425 0.85 MAPT (0.67) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL10420203 0.85 MAPT (0.65) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL80364 0.84 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL29493002 0.84 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL13839771 0.84 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL3163174 0.83 MAPT (0.72) MAPTKDM4ETHRBSMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4077464-B1 FREE RADICAL POLYMERIZABLE ADHESION-PROMOTING INTERLAYER COMPOSITIONS AND METHODS OF USE PRC DESOTO INT INC (US) 2026-04-29 EP disclosed
EP-4294856-A1 COMPOSITIONS CONTAINING A FREE RADICAL POLYMERIZATION INITIATOR PRC-Desoto International, Inc. (US) 2023-12-27 EP disclosed
EP-4077464-A2 FREE RADICAL POLYMERIZABLE ADHESION-PROMOTING INTERLAYER COMPOSITIONS AND METHODS OF USE PRC-Desoto International, Inc. (US) 2022-10-26 EP disclosed
CN-115244102-A Free radical polymerizable adhesion promoting interlayer compositions and methods of use PRC-迪索托国际公司 2022-10-25 CN disclosed
CN-115087711-A Adhesion promoting compositions containing organotitanates/zirconates and methods of use PRC-迪索托国际公司 2022-09-20 CN disclosed
WO-2022177863-A1 COMPOSITIONS CONTAINING A FREE RADICAL POLYMERIZATION INITIATOR PRC-DESOTO INTERNATIONAL, INC. (US) 2022-08-25 WO disclosed
CN-110719928-B Dual cure sealant PRC-迪索托国际公司 2022-08-12 CN disclosed
EP-3990265-A1 METHODS FOR MANUFACTURING WIND TURBINE BLADES AND LEADING EDGE PROTECTION SURFACES PPG Coatings Europe B.V. (NL) 2022-05-04 EP disclosed