SCHEMBL2397763

SCHEMBL2397763

Cc1cc2c(cc1C)C(C)(C)C1(C=Nc3c(ccc4ncccc34)O1)N2C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.54
KDM4E B2RXH2 5/20 0.54
THRB P10828 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
ALOX12 P18054 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
PKM P14618 1/20 0.54
LMNA P02545 4/20 0.48
HTT P42858 3/20 0.48
GAA P10253 3/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
RECQL P46063 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
POLB P06746 1/20 0.48
MAPK1 P28482 1/20 0.48
NPSR1 Q6W5P4 3/20 0.46
BLM P54132 2/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2401836 0.88 KDM4E (0.44) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL8717639 0.88 KDM4E (0.43) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL7117468 0.86 MAPT (0.72) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL29493000 0.86 MAPT (0.72) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL10420203 0.84 MAPT (0.65) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL2401558 0.84 MAPT (0.76) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL10552518 0.83 MAPT (0.55) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL10668429 0.83 MAPT (0.48) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL10419692 0.82 MAPT (0.41) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL9869228 0.80 MAPT (0.57) MAPTKDM4ETHRBSMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0141407-B1 PHOTOCHROMIC COMPOUND AND ARTICLES CONTAINING THE SAME PPG INDUSTRIES, INC. (US) 1988-06-15 EP claimed
EP-0141407-A2 Photochromic compound and articles containing the same PPG INDUSTRIES, INC. (US) 1985-05-15 EP claimed
EP-1404768-B1 POLYURETHANE BASED BALLPOINT INKS BIC CORP (US) 2020-04-22 EP disclosed
US-10249693-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-02 US disclosed
US-20140231780-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2014-08-21 US disclosed
US-8729793-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2014-05-20 US disclosed
US-8508121-B2 Organic light-emitting display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2013-08-13 US disclosed
EP-1394595-B1 PLASTIC MOLDED PRODUCT HAVING PHOTOCHROMIC CHARACTERISTICS AND/OR POLARIZING CHARACTERISTICS MITSUBISHI GAS CHEMICAL CO (JP) 2013-05-01 EP disclosed
US-20110291552-A1 ORGANIC LIGHT-EMITTING DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2011-12-01 US disclosed
US-20110228510-A1 OPTICAL FILTER AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-09-22 US disclosed
US-7118806-B2 Plastic molded product having photochromic characteristic and/or polarizing characteristics MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-10-10 US disclosed
US-6986946-B2 Transparent synthetic resin laminate having photochromism MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-01-17 US disclosed
US-20030055127-A1 Polyurethane based inks for writing instruments BIC CORPORATION 2003-03-20 US disclosed
US-6503965-B1 Ink composition comprising nonfluorescent pigment predispersed in alkyd resin, high boiling point hydrocarbon solvent, and stabilizer selected from antioxidants and antiskinning agents, which prevents alkyd resin from polymerizing BIC CORPORATION 2003-01-07 US disclosed
US-20020197484-A1 Transparent synthetic resin laminate having photochromism MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-12-26 US disclosed
US-5208132-A Microencapsulation of hindered amines MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1993-05-04 US disclosed