Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30657448 | 0.97 | STAT3 (0.40) | STAT3STAT1 | |
| SCHEMBL9430673 | 0.97 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL30821407 | 0.97 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL6517023 | 0.97 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL6744970 | 0.97 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL29430977 | 0.97 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL15809 | 0.97 | STAT3 (0.42) | STAT3STAT1 | |
| SCHEMBL705768 | 0.95 | STAT3 (0.41) | STAT3STAT1 | |
| SCHEMBL9717057 | 0.95 | STAT3 (0.41) | STAT3STAT1 | |
| SCHEMBL21729 | 0.95 | STAT3 (0.41) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11286271-B2 | Iridium (III) complexes containing N-heterocyclic carbene ligand, synthesis, and their use thereof in cancer treatment | THE UNIVERSITY OF HONG KONG (HK) | 2022-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11286271-B2 | Iridium (III) complexes containing N-heterocyclic carbene ligand, synthesis, and their use thereof in cancer treatment | HCCS, CASP3, BAD | STAT3 160/4885STAT1 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.