Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727843 | 1.00 | HTT (0.42) | HTTKMT2AGAAMAPTCA1 | |
| SCHEMBL18803134 | 0.81 | HTT (0.41) | HTTKMT2AGAAMAPT | |
| SCHEMBL23647988 | 0.77 | HTT (0.38) | HTTKMT2A | |
| SCHEMBL19229126 | 0.77 | HTT (0.38) | HTTKMT2A | |
| SCHEMBL19229125 | 0.77 | HTT (0.38) | HTTKMT2A | |
| SCHEMBL30206252 | 0.74 | KDM4E (0.39) | HTTKMT2AGAAMAPTCA1 | |
| SCHEMBL29354307 | 0.74 | ALDH1A1 (0.36) | HTTKMT2AGAAMAPTCA1 | |
| SCHEMBL29173696 | 0.74 | KDM4E (0.39) | HTTKMT2AGAAMAPTCA1 | |
| SCHEMBL3487390 | 0.74 | ALDH1A1 (0.36) | HTTKMT2AGAAMAPTCA1 | |
| SCHEMBL18232339 | 0.72 | TBK1 (0.38) | HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456355-B | Double-pyridine triazole semiconductor polymer and preparation and application thereof | 中国科学院化学研究所 | 2023-03-24 | — | — | CN | claimed |
| CN-114456355-A | Double-pyridine triazole semiconductor polymer and preparation and application thereof | 中国科学院化学研究所 | 2022-05-10 | — | — | CN | claimed |
| CN-114409682-A | Triazole pyridine receptor with positioning effect, polymer thereof and application thereof | 中国科学院化学研究所 | 2022-04-29 | — | — | CN | claimed |
| WO-2026101098-A1 | DICHROIC DYE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL CELL, AND LIQUID CRYSTAL DISPLAY DEVICE | 주식회사 엘지화학 | 2026-05-15 | — | — | WO | disclosed |
| CN-120040445-A | Heterocyclopyridine-7-one compound and medical application thereof | 浙江大学金华研究院 | 2025-05-27 | — | — | CN | disclosed |
| CN-113923988-B | Substituted arylmethyl ureas and heteroarylmethyl ureas, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2024-12-13 | — | — | CN | disclosed |
| EP-4373817-A1 | SUBSTITUTED PYRAZINE-2-CARBOXAMIDES AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER | Astrazeneca AB (SE) | 2024-05-29 | — | — | EP | disclosed |
| WO-2024105563-A1 | SUBSTITUTED BICYCLIC PYRIDONE DERIVATIVES | PFIZER INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| CN-117693503-A | Substituted pyrazine-2-carboxamides as HPK1 inhibitors for the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117327075-A | Bicyclic compounds as allosteric SHP2 inhibitors | 锐新医药公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-110446709-B | Bicyclic compounds as allosteric SHP2 inhibitors | 锐新医药公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-4175957-A1 | 2,3-DISUBSTITUTED PYRIDO[3,4-B]PYRAZINE-CONTAINING COMPOUNDS AS KINASE INHIBITORS | Purdue Research Foundation (US) | 2023-05-10 | — | — | EP | disclosed |
| CN-114456355-B | Double-pyridine triazole semiconductor polymer and preparation and application thereof | 中国科学院化学研究所 | 2023-03-24 | — | — | CN | disclosed |
| WO-2023001794-A1 | SUBSTITUTED PYRAZINE-2-CARBOXAMIDES AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2023-01-26 | — | — | WO | disclosed |
| CN-110655639-B | Segmented copolymer containing pyridine heterocyclic unit and preparation method and application thereof | 华南理工大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-114456355-A | Double-pyridine triazole semiconductor polymer and preparation and application thereof | 中国科学院化学研究所 | 2022-05-10 | — | — | CN | disclosed |
| CN-114409682-A | Triazole pyridine receptor with positioning effect, polymer thereof and application thereof | 中国科学院化学研究所 | 2022-04-29 | — | — | CN | disclosed |
| CN-110655653-B | A-D-A type polymer with main chain containing metal element, preparation method and application thereof | 华南理工大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-114195781-A | Pyridopyrazine compound and preparation method and application thereof | 安徽秀朗新材料科技有限公司 | 2022-03-18 | — | — | CN | disclosed |