Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 1.00 |
| ▸ | MAPK13 | O15264 | 14/20 | 1.00 |
| ▸ | MAPK12 | P53778 | 14/20 | 1.00 |
| ▸ | MAPK11 | Q15759 | 14/20 | 1.00 |
| ▸ | RAF1 | P04049 | 9/20 | 1.00 |
| ▸ | BRAF | P15056 | 5/20 | 1.00 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.82 |
| ▸ | GCGR | P47871 | 6/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.77 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.77 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.77 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | CIT | O14578 | 1/20 | 0.77 |
| ▸ | GAK | O14976 | 1/20 | 0.77 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.77 |
| ▸ | BRD4 | O60885 | 1/20 | 0.77 |
| ▸ | GMNN | O75496 | 1/20 | 0.77 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469877 | 1.00 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL252964 | 0.92 | MAPK13 (0.85) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL15401173 | 0.92 | MAPK13 (0.85) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL9619859 | 0.92 | MAPK13 (0.85) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL18292488 | 0.92 | MAPK13 (0.85) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL5307418 | 0.92 | MAPK13 (0.85) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL12561713 | 0.91 | MAPK13 (0.83) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL31255400 | 0.91 | MAPK13 (0.83) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL7228717 | 0.91 | MAPK13 (1.00) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL2949385 | 0.91 | MAPK13 (1.00) | MAPK14MAPK13MAPK12MAPK11RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117562905-A | Maintenance of immune response during chemotherapy regimen | G1治疗公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-117530948-A | Maintenance of immune response during chemotherapy regimen | G1治疗公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-111837146-A | Excellent dosage regimen for G1T38 | G1治疗公司 | 2020-10-27 | — | — | CN | disclosed |