Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494425 | 0.89 | MEN1 (0.64) | MEN1KMT2ANPC1ALDH1A1ALOX12 | |
| SCHEMBL29494232 | 0.86 | HSD17B10 (0.58) | MEN1KMT2ANPC1ALDH1A1ALOX12 | |
| SCHEMBL29494334 | 0.82 | NPC1 (0.65) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL20830056 | 0.79 | HPGD (0.72) | MEN1KMT2ANPC1ALDH1A1TDP1 | |
| SCHEMBL29494509 | 0.76 | NOTUM (0.47) | NPC1MAPTRAB9A | |
| SCHEMBL108168 | 0.73 | KMT2A (0.81) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL8209522 | 0.73 | TDP1 (0.60) | MEN1KMT2ANPC1ALDH1A1TDP1 | |
| SCHEMBL10107753 | 0.73 | ALDH2 (0.73) | MEN1KMT2ANPC1ALDH1A1TDP1 | |
| SCHEMBL29494480 | 0.72 | MEN1 (0.42) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL20828646 | 0.72 | HPGD (0.73) | MEN1KMT2AALDH1A1ALOX12TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | claimed |
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | disclosed |