Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | LDLR | P01130 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494467 | 0.88 | BAZ2B (0.44) | MEN1KMT2ALMNAALDH1A1NPC1 | |
| SCHEMBL29494419 | 0.82 | SMN1; SMN2 (0.40) | MEN1KMT2AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL29494276 | 0.72 | MEN1 (0.62) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL29494344 | 0.72 | BAZ2B (0.49) | LMNAALDH1A1NPC1RAB9APOLB | |
| SCHEMBL29494503 | 0.70 | HDAC1 (0.44) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL29494547 | 0.69 | RAB9A (0.48) | MEN1KMT2ALMNAALDH1A1NPC1 | |
| SCHEMBL29494509 | 0.69 | NOTUM (0.47) | NPC1RAB9AMAPT | |
| SCHEMBL29494535 | 0.69 | KLKB1 (0.49) | MEN1KMT2ALMNAALDH1A1NPC1 | |
| SCHEMBL29494461 | 0.69 | BLK (0.50) | MEN1KMT2ALMNAALDH1A1BCHE | |
| SCHEMBL22065282 | 0.66 | POLB (0.56) | MEN1KMT2ALMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | disclosed |