Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297224 | 0.85 | MEN1 (0.60) | TDP1PKMHPGDMEN1KMT2A | |
| SCHEMBL29494425 | 0.84 | MEN1 (0.64) | NPC1TDP1PKMHPGDMEN1 | |
| SCHEMBL20830056 | 0.84 | HPGD (0.72) | NPC1TDP1PKMHPGDMEN1 | |
| SCHEMBL29494276 | 0.82 | MEN1 (0.62) | NPC1TDP1PKMHPGDMEN1 | |
| SCHEMBL8209522 | 0.80 | TDP1 (0.60) | NPC1TDP1PKMHPGDMEN1 | |
| SCHEMBL29494232 | 0.79 | HSD17B10 (0.58) | NPC1TDP1PKMHPGDMEN1 | |
| SCHEMBL2937877 | 0.79 | SMN1; SMN2 (0.70) | NPC1TDP1HPGDMEN1KMT2A | |
| SCHEMBL10107753 | 0.78 | ALDH2 (0.73) | NPC1TDP1HPGDMEN1KMT2A | |
| SCHEMBL5337652 | 0.77 | ALDH1A1 (0.71) | NPC1TDP1HPGDMEN1KMT2A | |
| SCHEMBL8207225 | 0.77 | HPGD (0.60) | NPC1TDP1PKMHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | claimed |
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | disclosed |