Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.52 |
| ▸ | KLK1 | P06870 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494496 | 0.84 | MAPT (0.50) | KLKB1KLK1HPGDALDH1A1RAB9A | |
| SCHEMBL29494535 | 0.83 | KLKB1 (0.49) | KLKB1KLK1HPGDALDH1A1RAB9A | |
| SCHEMBL29494549 | 0.80 | KLKB1 (0.49) | KLKB1KLK1HPGDROCK2ROCK1 | |
| SCHEMBL2939268 | 0.79 | HPGD (0.64) | HPGDL3MBTL1ALDH1A1RAB9AKDM4E | |
| SCHEMBL29838366 | 0.76 | HPGD (0.63) | HPGDL3MBTL1ALDH1A1RAB9AMEN1 | |
| SCHEMBL18382971 | 0.75 | HTT (0.59) | HPGDL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL7723002 | 0.75 | HTT (0.67) | HPGDROCK2ROCK1L3MBTL1ALDH1A1 | |
| SCHEMBL29451525 | 0.75 | NPC1 (0.60) | HPGDL3MBTL1ALDH1A1RAB9AKDM4E | |
| SCHEMBL27412092 | 0.75 | HPGD (0.59) | HPGDL3MBTL1ALDH1A1RAB9AMEN1 | |
| SCHEMBL4241730 | 0.73 | KLKB1 (0.45) | KLKB1KLK1HPGDROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | disclosed |