Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | KLK1 | P06870 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494496 | 0.89 | MAPT (0.50) | KLKB1KLK1MEN1KMT2AMAPT | |
| SCHEMBL29494549 | 0.87 | KLKB1 (0.49) | KLKB1KLK1MEN1KMT2AMAPT | |
| SCHEMBL29494486 | 0.83 | KLKB1 (0.52) | KLKB1KLK1MEN1KMT2AMAPT | |
| SCHEMBL29494503 | 0.82 | HDAC1 (0.44) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL29494547 | 0.81 | RAB9A (0.48) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL29494461 | 0.74 | BLK (0.50) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2939268 | 0.71 | HPGD (0.64) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL29838366 | 0.71 | HPGD (0.63) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL29494552 | 0.71 | ADORA2A (0.43) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL15195531 | 0.70 | HPGD (0.60) | MEN1KMT2AMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | disclosed |