Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.49 |
| ▸ | KLK1 | P06870 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494535 | 0.87 | KLKB1 (0.49) | KLKB1KLK1HPGDMAPTLMNA | |
| SCHEMBL29494496 | 0.85 | MAPT (0.50) | KLKB1KLK1HPGDMAPTLMNA | |
| SCHEMBL29494485 | 0.83 | KCNH2 (0.45) | HPGDMAPTLMNAKCNH2KCNB1 | |
| SCHEMBL29494565 | 0.82 | KCNB1 (0.46) | HPGDMAPTLMNAMEN1KMT2A | |
| SCHEMBL29494486 | 0.80 | KLKB1 (0.52) | KLKB1KLK1HPGDMAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL29494303 | 0.78 | KCNB1 (0.41) | HPGDMAPTLMNAKCNH2KCNB1 | |
| SCHEMBL29494528 | 0.76 | BLK (0.47) | HPGDMAPTLMNAMEN1KMT2A | |
| SCHEMBL29494470 | 0.72 | METTL3 (0.43) | KLKB1KLK1MAPTMEN1KMT2A | |
| SCHEMBL24221413 | 0.71 | MMP2 (0.61) | MAPTMEN1POLBKMT2A | |
| SCHEMBL29494503 | 0.69 | HDAC1 (0.44) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | disclosed |