Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLK | P51451 | 2/20 | 0.52 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494537 | 0.91 | CLK1 (0.52) | BLKNSD2ADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL29494461 | 0.90 | BLK (0.50) | BLKNSD2ADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL29494528 | 0.86 | BLK (0.47) | BLKNSD2ADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL29494447 | 0.76 | MAPT (0.50) | BLKSMN1; SMN2BCHECYP2C9BTK | |
| SCHEMBL29494552 | 0.74 | ADORA2A (0.43) | ADORA2AADORA1SMN1; SMN2BCHEMEN1 | |
| SCHEMBL29494425 | 0.70 | MEN1 (0.64) | MEN1KMT2AHPGDALDH1A1LMNA | |
| SCHEMBL27382838 | 0.70 | ADORA2A (0.61) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL29191075 | 0.67 | MEN1 (0.54) | NSD2SMN1; SMN2CYP2C9MEN1KMT2A | |
| SCHEMBL30874538 | 0.67 | MEN1 (0.54) | NSD2SMN1; SMN2CYP2C9MEN1KMT2A | |
| SCHEMBL27489211 | 0.66 | MEN1 (0.71) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | disclosed |