Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494530 | 0.90 | NPC1 (0.51) | MAPTNPC1RAB9AGAAKCNH2 | |
| SCHEMBL29494547 | 0.90 | RAB9A (0.48) | MAPTNPC1RAB9AGAAKCNH2 | |
| SCHEMBL29494565 | 0.86 | KCNB1 (0.46) | MAPTNPC1RAB9AGAAKCNH2 | |
| SCHEMBL29494552 | 0.86 | ADORA2A (0.43) | MAPTNPC1RAB9AKCNH2KCNB1 | |
| SCHEMBL29494507 | 0.76 | BLK (0.52) | MAPTKCNH2KCNB1KDM4EALDH1A1 | |
| SCHEMBL29494503 | 0.76 | HDAC1 (0.44) | NPC1RAB9AKDM4EALDH1A1HTT | |
| SCHEMBL29494485 | 0.73 | KCNH2 (0.45) | MAPTNPC1RAB9AKCNH2KCNB1 | |
| SCHEMBL9365921 | 0.71 | KDM4E (0.51) | NPC1RAB9AGAAKDM4ELMNA | |
| SCHEMBL29494496 | 0.70 | MAPT (0.50) | MAPTNPC1RAB9AGAAKDM4E | |
| SCHEMBL29494535 | 0.70 | KLKB1 (0.49) | MAPTNPC1RAB9AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | disclosed |