Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494503 | 0.89 | HDAC1 (0.44) | ADORA2ANPC1RAB9AHDAC1HDAC2 | |
| SCHEMBL29494447 | 0.86 | MAPT (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL29494485 | 0.86 | KCNH2 (0.45) | ADORA2ANPC1RAB9AHDAC1HDAC2 | |
| Trifluoroacetic Acid SCHEMBL29494303 | 0.81 | KCNB1 (0.41) | ADORA2ANPC1RAB9AHDAC1HDAC2 | |
| SCHEMBL29494530 | 0.76 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL29494547 | 0.76 | RAB9A (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL29494507 | 0.74 | BLK (0.52) | ADORA2AADORA1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL29494565 | 0.73 | KCNB1 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL15578063 | 0.71 | HDAC1 (0.61) | ADORA2AHDAC1HDAC2ADORA1ALDH1A1 | |
| SCHEMBL29494496 | 0.71 | MAPT (0.50) | NPC1RAB9AADORA1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | disclosed |