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IGFBP2

Insulin-like growth factor-binding protein 2 · P18065 · IGFBP2 on Sugi Atlas →

48 patent compounds predicted against IGFBP2, 34 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL10923514 SCHEMBL10923514 0.47 2/20
SCHEMBL29360098 SCHEMBL29360098 0.47 2/20
SCHEMBL21979549 SCHEMBL21979549 0.46 2/20
SCHEMBL30514356 SCHEMBL30514356 0.46 2/20
SCHEMBL5825926 SCHEMBL5825926 0.44 2/20
SCHEMBL29997546 SCHEMBL29997546 0.44 2/20
SCHEMBL29752092 SCHEMBL29752092 0.40 2/20
SCHEMBL22475758 SCHEMBL22475758 0.35 2/20
SCHEMBL29857355 SCHEMBL29857355 0.35 2/20
SCHEMBL6014808 SCHEMBL6014808 1.00 1/20
SCHEMBL29930436 SCHEMBL29930436 1.00 1/20
Water Water (SCHEMBL31319504) 0.97 1/20
SCHEMBL1758192 SCHEMBL1758192 0.50 1/20
SCHEMBL9217699 SCHEMBL9217699 0.46 1/20
SCHEMBL724972 SCHEMBL724972 0.45 1/20
SCHEMBL11374392 SCHEMBL11374392 0.45 1/20
SCHEMBL21935558 SCHEMBL21935558 0.45 1/20
Benzoic Acid Benzoic Acid (SCHEMBL27538220) 0.44 1/20
SCHEMBL8834235 SCHEMBL8834235 0.44 1/20
SCHEMBL19003399 SCHEMBL19003399 0.44 1/20

Clinical trials — most relevant to IGFBP2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of Cytokines on Growth of Children With Chronic Kidney Failure PHASE4SUSPENDED
Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer PHASE4WITHDRAWN
Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis PHASE4COMPLETED
Insulin-like Growth Factor (IGF-I) in Hemodialysis Patients PHASE4COMPLETED
Efficacy of Oral Metformin vs Oral Doxycycline in Treating Acne Vulgaris PHASE4COMPLETED
Effect of Continuous GHRP-3 Infusion at on GH-IGF-I System, Blood Pressure, Glucose, and Insulin Resistance PHASE1/PHASE2WITHDRAWN
Study Assessing Potential Predictive Tumor Markers in Metastatic Colorectal Cancer PHASE2COMPLETED
Defined Green Tea Catechins in Treating Patients With Prostate Cancer Undergoing Surgery to Remove the Prostate PHASE1COMPLETED
Pappalysin 2 (PAPP-A2) Enzyme Replacement PHASE1COMPLETED
Prognostic Value of Protein IMP3 Expression in Cervical Cancer nanCOMPLETED
Biomarkers in the Diagnosis and Prognosis of NAFLD nanRECRUITING
Acute Kidney Injury - Biomarkers in Major Abdominal Surgery nanCOMPLETED
Epidemiology of Insulin Growth Factor (IGF) and Cardiovascular Events nanCOMPLETED
Metabolic and Inflammatory Responses to Hemodialysis and the Effect of a Meal nanCOMPLETED
A Low-Insulinemic Dietary Intervention to Reduce Breast Cancer Risk in High-Risk Women nanCOMPLETED
Assessment of the Diagnostic Role of Serum Insulin-like Growth Factor Binding Protein-3 as a Potential Biomarker for Colorectal Cancer (CRC) in Egypt nanNOT_YET_RECRUITING
Follow-up to Adult Height of a Cohort of Subjects Born Small for the Gestational Age and Treated With Growth Hormone nanCOMPLETED
Short-Term Fasting Before Chemotherapy in Treating Patients With Cancer nanCOMPLETED
Adipocytokines in Endometrial Cancer nanCOMPLETED
Using IGF-1 for Nutritional Monitoring nanCOMPLETED
Can Do Versus Do Do in Patients With Breast Cancer nanCOMPLETED
To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in the UK nanCOMPLETED
Genetic Study of Insulin-Like Growth Factor-I Receptor Mutations in Patients With Intrauterine Growth Retardation nanUNKNOWN
Effects of Standardized Meals on the Metabolic, Hormonal and Inflammatory Responses in Human nanCOMPLETED
TIMP2*IGFBP7 and Transient AKI nanCOMPLETED
DianaWeb: Before and After Study Online Based Participatory Research on Breast Cancer Women nanRECRUITING
IGF and Other Neurotrophic Factors in Patients With Dementia nanCOMPLETED
Role of Biomarkers in Endometrial Cancer Recurrence in Samples From Patients With Stage II, Stage III, or Stage IV Endometrial Cancer nanUNKNOWN
Metabolic and Hormonal Effects of 5:2 Intermittent Fasting nanCOMPLETED
IGF-I Induced Muscle Glucose Uptake and Interstitial IGF-I Concentrations nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a IGFBP2 binder may also engage these)

ProteinNameSimilarity
Q29400 — 1.000 Q29400 →
P24853 — 1.000 P24853 →
P47877 — 1.000 P47877 →
P13384 — 1.000 P13384 →
P49705 — 1.000 P49705 →
P12843 — 1.000 P12843 →
Q5XHC5 — 0.993 Q5XHC5 →
A4IIA2 — 0.992 A4IIA2 →
P20959 — 0.990 P20959 →
P47878 — 0.990 P47878 →
Q6Q484 — 0.988 Q6Q484 →
IGFBP3 Insulin-like growth factor-binding protein 3 0.988 landscape →
P21743 — 0.987 P21743 →
P47876 — 0.986 P47876 →
P47879 — 0.986 P47879 →
P21744 — 0.986 P21744 →
Q75ZP3 — 0.986 Q75ZP3 →
P15473 — 0.984 P15473 →
P24591 — 0.983 P24591 →
IGFBP5 Insulin-like growth factor-binding protein 5 0.983 landscape →
Q05716 — 0.982 Q05716 →
Q28985 — 0.982 Q28985 →
IGFBP6 Insulin-like growth factor-binding protein 6 0.982 landscape →
IGFBP4 Insulin-like growth factor-binding protein 4 0.982 landscape →
P24854 — 0.981 P24854 →
P24594 — 0.981 P24594 →
Q05718 — 0.981 Q05718 →
Q05717 — 0.978 Q05717 →
IGFBP1 Insulin-like growth factor-binding protein 1 0.977 landscape →
P47880 — 0.977 P47880 →