Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.67 |
| ▸ | P2RY6 | Q15077 | 7/20 | 0.64 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.64 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | TK2 | O00142 | 2/20 | 0.48 |
| ▸ | TK1 | P04183 | 1/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551997 | 0.90 | PYGM (0.55) | PYGMP2RY6P2RY14DNPH1NT5E | |
| SCHEMBL21551984 | 0.88 | PYGM (0.53) | PYGMP2RY6P2RY14DNPH1TK2 | |
| SCHEMBL7152602 | 0.86 | PYGM (0.67) | PYGMP2RY6P2RY14DNPH1NT5E | |
| SCHEMBL5315376 | 0.86 | DNPH1 (0.51) | PYGMP2RY6P2RY14DNPH1NT5E | |
| SCHEMBL6839765 | 0.84 | PYGM (0.82) | PYGMP2RY6P2RY14DNPH1TK2 | |
| SCHEMBL27778954 | 0.84 | P2RY6 (0.48) | PYGMP2RY6P2RY14DNPH1NT5E | |
| SCHEMBL1756171 | 0.82 | P2RY6 (0.80) | PYGMP2RY6P2RY14DNPH1NT5E | |
| SCHEMBL16672164 | 0.82 | P2RY6 (0.80) | PYGMP2RY6P2RY14DNPH1NT5E | |
| SCHEMBL12018429 | 0.82 | P2RY6 (0.80) | PYGMP2RY6P2RY14DNPH1NT5E | |
| SCHEMBL10132974 | 0.82 | P2RY6 (0.80) | PYGMP2RY6P2RY14DNPH1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983077-A1 | DELIVERY OF OLIGONUCLEOTIDES TO THE STRIATUM | Alnylam Pharmaceuticals, Inc. (US) | 2022-04-20 | — | — | EP | disclosed |