Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | ADH5 | P11766 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26865606 | 1.00 | HTT (0.62) | HTTHDAC1CYP11B1CYP11B2MAPT | |
| SCHEMBL26614109 | 0.89 | HTT (0.62) | HTTHDAC1CYP11B1CYP11B2MAPT | |
| SCHEMBL28722512 | 0.84 | HTT (0.55) | HTTHDAC1CYP11B1CYP11B2MAPT | |
| SCHEMBL27480025 | 0.84 | HTT (0.62) | HTTCYP11B1CYP11B2MAPTALDH1A1 | |
| SCHEMBL26614180 | 0.83 | ADH5 (0.54) | HTTHDAC1CYP11B1CYP11B2MAPT | |
| SCHEMBL8425351 | 0.83 | MAPT (0.51) | HTTHDAC1CYP11B1CYP11B2MAPT | |
| SCHEMBL1239741 | 0.81 | HTT (0.62) | HTTCYP11B1CYP11B2MAPTALDH1A1 | |
| SCHEMBL26865466 | 0.80 | MAPT (0.61) | HTTCYP11B1CYP11B2MAPTALDH1A1 | |
| SCHEMBL29495258 | 0.80 | MAPT (0.61) | HTTCYP11B1CYP11B2MAPTALDH1A1 | |
| SCHEMBL26614095 | 0.77 | MAPT (0.61) | HTTCYP11B1CYP11B2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423753-B | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114423753-A | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2022-04-29 | — | — | CN | disclosed |