Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247557 | 0.82 | CASP3 (0.55) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL22422804 | 0.82 | NR4A1 (0.50) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL30173208 | 0.82 | CASP3 (0.55) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL17134284 | 0.82 | CASP3 (0.55) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL10782350 | 0.81 | NR4A1 (0.46) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL13351546 | 0.81 | NR4A1 (0.46) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL25370110 | 0.79 | FURIN (0.50) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL28437338 | 0.77 | NR4A1 (0.55) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL16373451 | 0.77 | NR4A1 (0.50) | NR4A1NR4A2NR4A3PLK1MMP3 | |
| SCHEMBL3255960 | 0.76 | NR4A1 (0.58) | NR4A1NR4A2NR4A3PLK1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072975-A1 | COMPOSITIONS AND METHODS OF TREATMENT FOR SARS-COV-2 THROUGH PAPAIN PROTEASE INHIBITION | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2022-04-07 | — | — | WO | disclosed |