SCHEMBL3255960

SCHEMBL3255960

C[C](c1cccc2ccccc12)c1cccc2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.58
NR4A2 P43354 1/20 0.58
NR4A3 Q92570 1/20 0.58
PLK1 P53350 1/20 0.55
MMP3 P08254 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
CDC25B P30305 2/20 0.50
PTPN1 P18031 1/20 0.50
PTK2B Q14289 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ALDH1A1 P00352 4/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2A6 P11509 2/20 0.48
TDP1 Q9NUW8 3/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 2/20 0.47
GMNN O75496 2/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 2/20 0.47
MAPT P10636 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5012402 0.87 NR4A1 (0.55) NR4A1NR4A2NR4A3PLK1MMP3
SCHEMBL66680 0.85 NR4A1 (0.58) NR4A1NR4A2NR4A3PLK1MMP3
SCHEMBL3107442 0.84 NR4A1 (0.63) NR4A1NR4A2NR4A3PLK1MMP3
SCHEMBL18139677 0.84 PTK2B (0.53) NR4A1NR4A2NR4A3PLK1MMP3
SCHEMBL8034961 0.83 NR4A1 (0.56) NR4A1NR4A2NR4A3PLK1MMP3
SCHEMBL27486785 0.83 NR4A1 (0.61) NR4A1NR4A2NR4A3PLK1MMP3
SCHEMBL28048462 0.82 DEGS1 (0.50) NR4A1NR4A2NR4A3PLK1MMP3
SCHEMBL50651 0.81 NR4A1 (0.65) NR4A1NR4A2NR4A3PLK1MMP3
SCHEMBL273123 0.81 PTK2B (0.55) NR4A1NR4A2NR4A3PLK1MMP3
SCHEMBL29563474 0.81 PTK2B (0.55) NR4A1NR4A2NR4A3PLK1MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100125154-A1 PHOSPHORUS COMPOUND AND METHOD FOR PREPARING THE SAME CHANG CHUN PLASTIC CO., LTD. (TW) 2010-05-20 US claimed
EP-2186816-A1 Phosphorus compound and method for preparing the same Chang Chun Plastics Co., Ltd. (TW) 2010-05-19 EP claimed
CN-106432075-B Hydrogenated quinoline imine nickel complex catalyst containing benzhydrylnaphthalene and preparation method and application thereof 中国科学院化学研究所 2019-12-27 CN disclosed
US-8785696-B2 Phosphorus compound and method for preparing the same CHANGCHUN PLASTICS CO., LTD. (TW) 2014-07-22 US disclosed
US-20100125154-A1 PHOSPHORUS COMPOUND AND METHOD FOR PREPARING THE SAME CHANG CHUN PLASTIC CO., LTD. (TW) 2010-05-20 US disclosed
EP-2186816-A1 Phosphorus compound and method for preparing the same Chang Chun Plastics Co., Ltd. (TW) 2010-05-19 EP disclosed
US-20080207864-A1 Organosilanes, Process For Production of the Same, and Use Thereof SHARP KABUSHIKI KAISHA (JP) 2008-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100125154-A1 PHOSPHORUS COMPOUND AND METHOD FOR PREPARING THE SAME PHOSPHO1, PFAS, PPA1 NR4A1 2940/4885NR4A2 2639/4885NR4A3 3210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.