Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22969399 | 1.00 | HTR3A (0.42) | HTR3AADRB1PIK3CAMTORTRPV3 | |
| SCHEMBL29495986 | 0.89 | HTR3A (0.47) | HTR3AADRB1GAAMCHR1PDE10A | |
| SCHEMBL22969580 | 0.89 | HTR3A (0.47) | HTR3AADRB1GAAMCHR1PDE10A | |
| SCHEMBL22969615 | 0.84 | GAA (0.52) | HTR3AADRB1PIK3CAMTORCNR2 | |
| SCHEMBL29495731 | 0.84 | GAA (0.52) | HTR3AADRB1PIK3CAMTORCNR2 | |
| SCHEMBL29496148 | 0.84 | HTR3A (0.41) | HTR3AADRB1TRPV3CNR2GAA | |
| SCHEMBL22969511 | 0.82 | GAA (0.49) | HTR3AADRB1PIK3CAMTORCNR2 | |
| SCHEMBL29495910 | 0.82 | GAA (0.49) | HTR3AADRB1PIK3CAMTORCNR2 | |
| SCHEMBL22969237 | 0.78 | MCHR1 (0.49) | MCHR1 | |
| SCHEMBL29495695 | 0.78 | MCHR1 (0.49) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | claimed |
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | disclosed |