Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 3/20 | 0.37 |
| ▸ | ATR | Q13535 | 2/20 | 0.36 |
| ▸ | ATRIP | Q8WXE1 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22969511 | 1.00 | GAA (0.49) | GAAPIM1PIM2HTR3AMCHR1 | |
| SCHEMBL29495731 | 0.97 | GAA (0.52) | GAAPIM1PIM2HTR3AMCHR1 | |
| SCHEMBL22969615 | 0.97 | GAA (0.52) | GAAPIM1PIM2HTR3AMCHR1 | |
| SCHEMBL22969580 | 0.90 | HTR3A (0.47) | GAAHTR3AMCHR1ADRB1 | |
| SCHEMBL29495986 | 0.90 | HTR3A (0.47) | GAAHTR3AMCHR1ADRB1 | |
| SCHEMBL29496062 | 0.84 | GAA (0.48) | GAAPIM1PIM2HTR3ACCNC | |
| SCHEMBL22969277 | 0.83 | SHMT2 (0.42) | GAACCNCCDK8PIK3CAMTOR | |
| SCHEMBL29495961 | 0.83 | SHMT2 (0.42) | GAACCNCCDK8PIK3CAMTOR | |
| SCHEMBL22969399 | 0.82 | HTR3A (0.42) | GAAHTR3AMCHR1CNR2ADRB1 | |
| SCHEMBL29495813 | 0.82 | HTR3A (0.42) | GAAHTR3AMCHR1CNR2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | claimed |
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | disclosed |