SCHEMBL2949599

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29708208	0.89	VCAM1 (0.59)	ERN1VCAM1EGFRPOLBMEN1
	SCHEMBL4726931	0.89	VCAM1 (0.59)	ERN1VCAM1EGFRPOLBMEN1
	SCHEMBL19010023	0.87	ERN1 (0.61)	ERN1VCAM1EGFRPOLBMEN1
	SCHEMBL497490	0.85	ERN1 (0.55)	ERN1VCAM1EGFRPOLBMEN1
	SCHEMBL498267	0.84	KDM4E (0.54)	ERN1VCAM1EGFRPOLBMEN1
	SCHEMBL13011322	0.83	VCAM1 (0.53)	VCAM1MEN1KMT2ANPC1RAB9A
	SCHEMBL13011315	0.82	VCAM1 (0.55)	VCAM1POLBMEN1KMT2AMAPT
	SCHEMBL18980914	0.82	ERN1 (0.49)	ERN1VCAM1EGFRPOLBMEN1
	SCHEMBL17197998	0.81	VCAM1 (0.61)	ERN1VCAM1POLBMEN1KMT2A
	SCHEMBL12181970	0.81	POLB (0.55)	ERN1VCAM1POLBMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.