SCHEMBL498267

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4726931	0.89	VCAM1 (0.59)	KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL29708208	0.89	VCAM1 (0.59)	KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL19010023	0.87	ERN1 (0.61)	MAPTCA1CA2ERN1MEN1
	SCHEMBL2336139	0.85	HTR7 (0.56)	KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL497490	0.85	ERN1 (0.55)	MAPTCA1CA2ERN1MEN1
	SCHEMBL2949599	0.84	ERN1 (0.51)	MAPTERN1MEN1KMT2AMAPK1
	SCHEMBL27530424	0.83	MAPT (0.67)	KDM4EMAPTALDH1A1MEN1KMT2A
	SCHEMBL11188343	0.83	HTR7 (0.54)	KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
	SCHEMBL5147211	0.82	MAPT (0.54)	KDM4ECYP1A2CYP2C9CYP2C19MAPT
	SCHEMBL18980914	0.82	ERN1 (0.49)	MAPTALDH1A1ERN1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.