Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PDE8A | O60658 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22969280 | 0.82 | MCHR1 (0.42) | HTR1ADRD2HTR2AHTR7MCHR1 | |
| SCHEMBL29495748 | 0.82 | MCHR1 (0.42) | HTR1ADRD2HTR2AHTR7MCHR1 | |
| SCHEMBL29496060 | 0.73 | PARP1 (0.40) | PARP1MCHR1 | |
| SCHEMBL28248838 | 0.72 | MCHR1 (0.43) | PDE8AHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL29495693 | 0.71 | MCHR1 (0.40) | PDE8AHTR1ADRD2MCHR1CHRNA7 | |
| SCHEMBL22969284 | 0.71 | MCHR1 (0.40) | PDE8AHTR1ADRD2MCHR1CHRNA7 | |
| SCHEMBL29496056 | 0.71 | KDM4E (0.37) | PARP1 | |
| SCHEMBL9974286 | 0.70 | DRD2 (0.48) | PDE8AHTR1ADRD2HTR2AHTR7 | |
| SCHEMBL29496062 | 0.70 | GAA (0.48) | CNR2 | |
| SCHEMBL29496148 | 0.69 | HTR3A (0.41) | PARP1TRPV3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | disclosed |